Various stimuli have been proposed to be responsible for the feeding-induced stimulation of MPS, including insulin mediated via changes in local blood flow (Fujita et al., 2006b, 2007), and leucine via stimulation of the mammalian target of rapamycin complex 1 (m TORC1) (Crozier et al., 2005). Many studies of the regulation of MPS in humans have been carried out in young men and a variety of nutritional and contractile variables have been studied.
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INTRODUCTION It is well known that the ingestion of protein or amino acids results in increased plasma amino acid levels (hyperaminoacidemia) that stimulate muscle protein synthesis (MPS) and that resistance exercise increases this feeding-induced stimulation of MPS even more (Breen & Phillips, 2012).
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